Do any necessary filling with spackle, wood dough or Magic Sculp (Magic Sculp is best used on a Magic Sculp casting usually), additional sanding, etc. Wipe off the dust with a 'tac rag' and spray more primer when finished. Sometimes a primer is not needed. Always do a test. Make sure primer is compatible with casting material and that the paint will stick to the primer. Test to see if you even need a primer.
Save the cut out mouth area. This will be used later to make a jaw assembly.